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Domenii publicaţii > Fizica + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: M. A. Calin, R. M. Ion, N. Herascu

Editorial: Journal of Optoelectronics and Advanced Materials, 7(6), p.3155-3160, 2005.


Photodynamic therapy is a local treatment modality of cancer, based on the
administration of photosensitizer, which is selectively retained al tumoral level, and
which after the optical radiations exposure lead to the tumoral tissue destruction. The
application of the photodynamic therapy in clinical practice presents many problems. The
present study aims to correlate the refraction indices of the tumoural tissue with
refractive indices of photosensitizer solutions and optical radiation distribution at
tumoral level. There were used diffuse reflection spectrophotometry and molecular
absorption spectrophotometry for the characterization of the optical properties of certain
photosensitizer and the Kramers-Kronig analysis for the determination of the refraction
indices of the solutions.

Cuvinte cheie: Porphyrin, Photodynamic terapy, Cancer, Photosensitizer, Diffuse reflection