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Degradarea fotochimica a riboflavinei utilizata ca medicament in terapia fotodinamica

Domenii publicaţii > Chimie + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: Rodica-Mariana ION, Alexandru-Marcel IONITA, Benone CARSTOCEA

Editorial: Revista de Chimie, 57(7), p.718-721, 2006.

Rezumat:

A study of the effect of light on photodegradation reactions of riboflavin (RF) solutions in the presence of phosphate buffer has been made in this paper. Photodegradation is facilitated by UV radiation and yields to lumichrome (LC) and lumiflavin (LF). Some aspects concerning the RB dimerization and photoproducts identification (by chromatography coupled with mass spectrometry) are treated.

Cuvinte cheie: riboflavin; photodegradation; lumichrome; photochemistry