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Methylmethacrylate-Iodothiophene copolymers for the obtaining of bone and dental cements

Domenii publicaţii > Stiinte ingineresti + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: C. ZAHARIA, T. ZECHERU, E. RUSEN, A. SÃLÃGEANU, C. CINCU

Editorial: Journal of Optoelectronics and Advanced Materials, 9(11), p.3307-3311, 2007.

Rezumat:

This paperwork deals with the obtaining of a new radio-opaque biomaterial that can be used in the manufacture of bone or dental cements. We have obtained some radio-opaque copolymers based on methyl methacrylate (MMA) and 2-iodothiophene (ITf). The copolymers were characterised by Gel Permeation Chromatography and their molecular weights were obtained. Next, they were subjected to viscosity analysis to evaluate the K and α constants from Kuhn-Mark-Houwink-Sakurada equation. The values for the two constants showed an increase of the rigidity of the macromolecular chains, approaching as shape the model of the rigid rod. The biocompatibility of the copolymers was tested in vitro on an L929 cell line of murine fibroblasts and these materials revealed no cytotoxic effect upon the cells. These results combined with the excellent radio-opacity of the materials lead to the suggestion that this type of polymers could be used as dental or bone cements for the replacement of barium or zirconium particles usually added to provide X-ray opacity

Cuvinte cheie: cement, in vitro assays, PMMA, iodine-containing monomer