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Congenital malformation – a risk factor for infectious pathology

Domenii publicaţii > Ştiinţe medicale + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: V. Botiu, D. Iacob, M. Boia, M. Puiu, R. Iacob, A. Manea;

Editorial: nature publishing group, European journal of human genetics, Volume 14 Supplement 1, p.116, 2006.


Introduction: Congenital malformations represent a fundamental
pathology problem correlated to incidence, etiology, pathology and
medical and social implications.
Purpose: This study wants to establish the correlation between
congenital malformations of the newborns and the infections pathology
they developed.
Material and method: Clinical examinations and laboratory data have
been used for this study.
Results: Of a total number 2610 hospitalized new born 6,89% had
congenital malformations, 3,73% male and 3,54% female. The types
of malformations are cardiovascular 2,68%, gastrointestinal 0,28%,
the urinary tract 0,38%, central nervous system 0,38% and complexes
malformations 0,09%.
The infectious pathology of the new born is he following: skin and
mucous 4,02%, respiratory infection 3,64%, bacteremia 1,15% and
urinary infections 0,86%.
Of a total number of positive cultures we found staphylococcus
aureus 65,65%, e. colli 18,32%, enterobacter 6,87%, klebsiella
3,05%, staphylococcus R 3,05%, pseudomonas aeruginosa 2,29%,
staphylococcus epidermidis 0,76%.
Maternal infections circumstances: the premature rupture of the
amniotic membranes 22,22%, green amniotic fluid 30,55%, maternal
infections 19,44%.
Conclusions: 1. because of the immaturity of the imunitary system at the
new borns with congenital malformations, the infections pathology is
more frequent; 2. the most frequent bacterial agent are staphylococcus
aureus and e. colli.

Cuvinte cheie: malformatii congenitale, infectii, nou-nascut // congenital malformations* infectious pathology* newborn