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Transition metal effect on the structure of pyrazinamide complexes

Domenii publicaţii > Chimie + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: S.Simon, T.Jurca

Editorial: International Journal of modern Physics B, Vol 18, p.p.1-8, 2004.


Pyrazinamide (PZA) is among the first-line drugs for the treatment of tuberculosis, which seems to reappear as a frequent disease. In this study is investigate the thermal behaviour of new transition metal complexes of PZA and is searched for a correlation between structure and thermal transformations, described as multi-step processes consisting in crystaline phase transition, decomposition, melting and thermo-oxidation.

Cuvinte cheie: metale tranzitionale, pirazinamida, analiza termica // Transition metal, pyrazinamide, thermal analysis