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Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS.

Domenii publicaţii > Biologie + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: Wang J, Farr GW, Zeiss CJ, Rodriguez-Gil DJ, Wilson JH, Furtak K, Rutkowski DT, Kaufman RJ, Ruse CI, Yates JR 3rd, Perrin S, Feany MB, Horwich AL

Editorial: Proc Natl Acad Sci U S A., 106(5), p.1392-7, 2009.

Rezumat:

Cuvinte cheie: Amyotrophic Lateral Sclerosis/*genetics,Animals,Glial Fibrillary Acidic Protein/metabolism,Luminescent Proteins/*genetics, Mice, Mice, Transgenic, Molecular Chaperones/*metabolism, Motor Neurons/metabolism, Nucleic Acid Hybridization MH - Solubility MH - Spinal Cord/cytology/metabolism, Superoxide Dismutase/*genetics, Ubiquitin/metabolism

URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631083/?tool=pubmed