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CELLULAR AND MOLECULAR IMPACT OF LITHIUM AND LITHIUM MINERAL WATER MARIA FROM MALNAS-BAI ON GLIAL CELLS

Domenii publicaţii > Biologie + Tipuri publicaţii > Articol în volumul unei conferinţe

Autori: Muntenau C., Munteanu D., Zamfirescu G. & Zarnescu O.

Editorial: Abstract A236.13, published in FENS Forum Abstracts, Vol 3, 2006.

Rezumat:

Lithium exists in the biological tissues, aliments and running water. Spring waters contain great concentrations of lithium salts and other metal ions. Lithium salts have been first used with therapeutic purpose in 1850 for treating gout symptoms, rheumatism and renal Lithia. In 1949, Cade has the merit to discover the sedative effects of lithium salts on manic phase of affective disorders, but the therapy is accompanied with frequent cases of intoxication. In 1967, was possible the determination of therapeutic values of lithemia (0, 2 – 1, 5 mEq/l). In Romania are existing the sparking waters sources which have a high level of lithium salts in the content, being so-called Lithium content sparkling waters, the concentration of lithium being between 3 and 8 mg Li per liter. One of these sources is Maria spring from Malnas-Bai, which has a lithium concentration of 8, 03 mg lithium per liter Malnas is located in the Nordic extremity of Covasna district, in the Bixad depression, with highs between 570 and 650m. In the West part there is the Nordic Group of Bodoc Mountains, w ith highs of 1200 m. The aim of this study is to investigate the influence of lithium mineral waters upon the regulatory differentiation and proliferation of glial cells.

Cuvinte cheie: Neurological and psychiatric conditions

URL: http://fens2006.neurosciences.asso.fr/abstracts/R7/A236_13.html