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Interstitial cells of Cajal in the gut–a gastroenterologist’s point of view.

Domenii publicaţii > Ştiinţe medicale + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: Negreanu LM, Assor P, Mateescu B, Cirstoiu C.

Editorial: World J Gastroenterol. 2008 Nov 7;14(41):6285-8., 2008.

Rezumat:

Alterations of normal function of interstitial cells of Cajal (ICC) are reported in many intestinal disorders. Diagnosis of their involvement is rare (infrequent), but necessary to propose a specific treatment. This article reviews the place of ICC in the pathogenesis of achalasia, gastroesophageal reflux disease, infantile hypertrophic pyloric stenosis, chronic intestinal pseudo-obstruction and slow transit constipation. Moreover we discuss the role of the Cajal cells in the development of stromal tumors of the gastrointestinal tract.

Cuvinte cheie: Cajal cells; c-kit; Intestinal motility; Achalasia; Gastrointestinal stromal tumor

URL: http://www.wjgnet.com/1007-9327/14/6285.asp