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Effect of nano-topographical features of Ti/TiO2 electrode surface on cell response and electrochemical stability in artificial saliva

Domenii publicaţii > Chimie + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: I. Demetrescu, C. Pirvu, V. Mitran

Editorial: Bioelectrochemistry, 79 (1), p.122-129, 2010.


The paper is a new approach which aims to evaluate the relation between surface aspects (wettability and roughness) of materials based on titanium with native passive TiO2 as untreated samples and TiO2 nanotubes as treated discs respectively, their electrochemical stability in artificial saliva, and fibroblast cell behavior.

Ti/TiO2 modified electrodes as nanotubes with 120 nm as diameter were obtained using an electrochemical method as anodizing and surface analysis as SEM, AFM and contact angle measurements were performed to obtain topographical features and wettability.

The TiO2 nanotube structured oxide films electrochemical growth increases the stability of titanium surfaces. The electrochemical behavior of the Ti/TiO2 nanotube surface was evaluated by corrosion parameters obtained from Tafel plots and electrical parameters for proposed circuits from electrochemical impedance spectroscopy were analyzed.

The cell results indicated a slight preference in terms of cell survival and adhesion for nanostructure TiO2 with a more hydrophilic character and the electrochemical data revealed that such features are connected with better stability in artificial saliva. The roughness seems to be not conclusive for this case.

Cuvinte cheie: TiO2 nanotubes, biocompatibility