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Chemoenzymatic synthesis of both (R)- and (S)-aryl-1,2-ethanediols

Domenii publicaţii > Chimie + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: Bencze, L. C., Paizs, C., Tosa, M. I., Irimie, F. D., Rétey, J.

Editorial: WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, ChemCatChem, 3, p.343, 2011.

Rezumat:

A baker’s dozen: Optically active 1,2-ethanediols are important chiral building blocks in organic synthesis. A highly selective and efficient chemoenzymatic one-pot procedure has been developed for the synthesis of both enantiomers of various 1-aryl-1,2-ethanediols from the corresponding aryl ethanones by using baker’s yeast

Cuvinte cheie: alcoholi, sinteza chemoenzimatica, hidrolaze, sinteza one-pot, reactivi legati de polimer // alcohols, chemoenzymatic synthesis, hydrolase, one-pot synthesis, polymer-bound reagents

URL: http://http://onlinelibrary.wiley.com/doi/10.1002/cctc.201000295/pdf