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Tracheal telocytes

Domenii publicaţii > Ştiinţe medicale + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: Rusu MC, Jianu AM, Mirancea N, Didilescu AC, Manoiu VS, Paduraru D.

Editorial: Blackwell Publishing Ltd., J Cell Mol Med, 16(2), p.401-405, 2012.


Recently, a novel type of stromal cell – the telocytes (TC) – was identified in
mouse trachea. These cells are known to possess the ultrastructural characteristics which support their role in intercellular signaling. We found TC in all stromal compartments of the tracheal wall. TC with long prolongations(telopodes, Tp) were lining longitudinally the collagen bundles, and were serially arranged (end-to-end connections of Tp were found). Noteworthy, Tp frequently establish stromal synapses with mast cells (MC). Primary cilia were also identified in TC. In conclusion, tracheal TC could be involved in the
tracheal regulation (e.g. secretion, contractility). The tandem TC-MC deserves further investigations.

Cuvinte cheie: telocytes; telopodes; mast cells; interstitial cells; stromal cells; primary cilium.