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The effect of vitamins to hydroxyapatite growth on porous polyurethane substrate

Domenii publicaţii > Chimie + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: Gabriela Ciobanu, S. Ilisei, C. Luca, G. Carja, O. Ciobanu

Editorial: Elsevier, Progress in Organic Coatings, 74 (4), p.648-653, 2012.

Rezumat:

This work presents a study on the possibility of obtaining hydroxyapatite thin layers on porous
polyurethane support using a modified coating method, which is based on a biomimetic technique. To
investigate bone-like apatite coatings formation on polyurethane surface, two types of solutions such as
supersaturated calcification solution (SCS) and modified SCS (M-SCS) were used. The modified supersaturated
calcification solution was prepared with added at original SCS appropriate quantities of vitamin
A and vitamin D2. The hydroxyapatite deposits are investigated by scanning electron microscopy (SEM)
coupled with energy dispersive X-ray analysis (EDX) and ATR-IR spectroscopy. The presence of vitamins
(A and D2) in M-SCS solution favours the formation of hydroxyapatite layer on polymeric substrate. The
results obtained from SEM images have showed that porous polyurethane/hydroxyapatite scaffolds with
estimated porosity of over 60% in an interconnected network, were produced under vitamins influence.

Cuvinte cheie: hydroxyapatite, coatings, vitamins, porous polyurethane