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Cervical Intraepithelial Neoplasia in the „Dr. Salvator Vuia” Clinical Obstetrics and Gynecology Hospital – Arad During the 2000-2009 Period

Domenii publicaţii > Ştiinţe medicale + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: V. Daşcãu; Gh. Furãu; C. Furãu; L. Pãiuşan; Adriana Radu; Casiana Stãnescu

Editorial: MÆDICA - a Journal of Clinical Medicine, nr. 2/2012, p.138-142, 2012.


Objectives: This study intends to analyze some statistical data concerning Cervical Intraepithelial
Neoplasia diagnosed in our hospital.
Material and Methods: Our study concerning the incidence of Cervical Intraepithelial Neoplasia
(CIN) covers the 2000-2009 time-span, the data being collected from the Histopathology Exams (HPE)
Results: During this period, CIN lesions were discovered in 1256 cases and Cervical Intraglandular Dysplasia (CIGD) in 53 cases. CIN I, CIN II and CIN III lesions represented 65.92% (828 cases),
19.67% (247 cases), and 14.41% (181 cases) of the total CIN cases, respectively. There were 26 cases
combined with cervical carcinoma (2.07% of all CIN cases, 3.56% of the 731 cervical cancer cases). The
mean patients’ age was 44.65± 9.83 years for all cervical dysplasia cases, 44.58± 9.75 years for all CIN
cases, 43.81±9.22, 46.50±10.17, and 45.46±11.05 years for CIN I, CIN II, and CIN III, respectively, and
46.45 ± 11.63 years for CIGD. The t-test revealed the following significant differences: all cases versus
CIN I (p<0.05) and CIN II (p<0.01), CIGD versus CIN I (p<0.05), all cases versus CIN II (p<0.01), CIN I versus CIN II (p<0.0001) and versus CIN III (p<0.05). The mean age of the 731 cervical cancer cases diagnosed in our hospital during that same period was 52.94±12.96 years,and it was statistically significantly different from the mean ages of patients with CIN I, II and III (p <0.00000001) and with CIGD (p<0.0005). Conclusions: Early detection of CIN is of utmost importance for preventing cervical cancer, a serious and frequent health problem in Romania.

Cuvinte cheie: cervical intraepithelial neoplasia, cervical intraglandular dysplasia, cervical biopsy, cervical cancer