Autori: Lungu, N.C., Alexandroaei, M, Sandu I.
Editorial: Revista de chimie, 62, ( 8 ), p.787-791, 2011.
Penicillinase is the enzyme that inactivates the antibiotic, hydrolyzing
β-lactam nucleus and leading to
inactivation of biological product. In this study, we obtained a combined kinetics: chemical and enzymatic degradation of the penicillin in enzymatic aqueous medium. Thus, we have obtained kinetic parameters of β-lactamase action with attenuated activity on penicillin G, by the separation of the two effects.
Cuvinte cheie: β-lactamases, penicillinase