Scopul nostru este sprijinirea şi promovarea cercetării ştiinţifice şi facilitarea comunicării între cercetătorii români din întreaga lume.
Autori: Rusu MC, Loreto C, Manoiu VS
Editorial: Acta Histochem, 116(4), p.663-8, 2014.
The phenotypes of the temporomandibular joint (TMJ) disc cells range from fibroblasts to chondrocytes. There are relatively few reported studies using transmission electron microscopy (TEM) to determine the ultrastructural features of these cells. It was hypothesized that at least a subpopulation of TMJ stromal cells could be represented by the telocytes, cells with telopodes. In this regard a TEM study was performed on rat TMJ samples. Collagen-embedded networks were found built-up by cells with telopodes with subplasmalemmal caveolae, moderate content in matrix secretory organelles and well-represented intermediate filaments. Appositions of cell bodies were found. Prolongations of such cells were closely related to nerves and microvessels. Our study indicates that the TMJ disc attachment seems equipped with telocytes capable of stromal signaling. However, further studies are needed to assess whether the telocytes belong to a renewed cell population derived from circulating precursors.
Cuvinte cheie: CD34, CLCs, FCs, FLCs, Fibroblasts, ICCs, ICLCs, Interstitial Cajal cells, Interstitial Cajal-like cells, Interstitial cells of Cajal, Stromal signaling, TCs, TEM, TMJ, Temporomandibular joint, Tps, Transmission electron microscopy, chondrocyte-like cells, fibroblast-like cells, fibrochondrocytes, telocytes, telopods, temporomandibular joint, transmission electron microscope