Articolele autorului Dragos-Viorel Brezoi
Link la profilul stiintific al lui Dragos-Viorel Brezoi

New Nano-Sized Sensing Drug and Its Clinical Application

Nanomedicine is the application of nanotechnology to the diagnosis and treatment of human disease. This discipline has the potential to change medical science dramatically, for example as demonstrated by an innovation in cancer imaging that uses novel diagnostic agents synthesized from nanoparticles. Some research on cluster-based materials for future medical applications is described in this paper. The design of a multifunctional photosensitive

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A Study on the Photodynamic Therapy of Photosensitizer-Coated Magnetic Nanoparticles

One of the important points in the use of magnetic nanoparticles for biomedical applications is the encapsulation of the magnetic material, in order to make it biocompatible, producing a bio-ferrofluid. In this paper, ferrimagnetic particles of Fe3O4 were nanometrically synthesized. In order to coat a photosensitizer on the magnetic particles, TSPP was choosed and introduced into the ferrofluid suspension containing magnetite and the adsorption reaction

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Nanocomposites Based on Polypyrrole with Porphyrin -Oxodimer

Pyrroles represent a unique set of supramolecular "building blocks" that, depending on the nature and number of substituents, are capable of stabilizing a range of self-assembled entities in the solid state. In this paper, it has been prepared new molecular aggregates composed of a iron oxide and a functional polymer (polypyrrole) with oxo dimers of porphyrin spacers. The new system is characterized by FTIR, UV-Vis and SEM techniques. The particles

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Phase evolution induced by polypyrrole in iron oxide – polypyrrole nanocomposite

Nanocomposite of polypyrrole and iron oxide were prepared using simultaneous gelation and polymerization processes. Varied amounts of pyrrole were added to a solution containing an Fe(III) salt as precursor and 2-metoxy ethanol as solvent. The particles were found to be nanocrystalline. However, the composites exhibited mixed phase, belonging to both the corrundum α-Fe2O3 (nonmagnetic) and the cubic phase, Fe3O4, which is ferromagnetic. The presence

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‘Host-Guest’ Supramolecular Systems (Encapsulated Porphyrins in Macronets) with Biomedical Applications

The interaction of an anionic porphyrin meso-tetra(4-sulfonatophenyl)porphyrin (TSPP) with a polymeric sorbant resin called Macronet in aqueous solution, is investigated in this paper by spectral techniques: UV-Vis, IR. The polymric resins used in this paper MN150, MN250, have a porosity formed by micropors (14 Å) and mesopors (300-400 Å) which yield to a high specific surface: 900-1200 m2/g and a small pors volume: 0,6-0,8 ml/g. Due to the big

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Laser effect in photodynamic therapy of tumors

Photodynamic therapy is a method that provides a reasonable alternative to other treatment modalities for patients with certain cancers, and in some cases may be the preferred treatment. The therapy implies the intravenous administration of a light-sensitive substance, the photosensitizer. The used sensitizer must absorb at long wavelength. For these purposes, the carbon dioxide laser, He-Ne and the argon laser are particularly suitable. In this

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