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Articolele autorului Bogdan Dragos GrigoriuLink la profilul stiintific al lui Bogdan Dragos Grigoriu
Loss of Endocan tumorigenic properties after alternative splicing of exon 2
Background: Endocan was originally described as a dermatan sulfate proteoglycan found freely circulating in the blood. Endocan expression confers tumorigenic properties to epithelial cell lines or accelerate the growth of already tumorigenic cells. This molecule is the product of a single gene composed of 3 exons. Previous data showed that endocan mRNA is subject to alternative splicing with possible generation of two protein products. In the present
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