Bogdan Dragos Grigoriu

INSERM U774 and UMF IASI, IASI, .

E-mail: trimite un mesaj.

Nascut(a) in: 1967

Interese: endotelial cell, sepsis, cancer microenvironment, mesothelioma, tuberculosis, diagnostic marker

Details:
1. Markers of endothelial activation in cancer and sepsis patients
2. Tumor microenvironment and cancer progression

3. Diagnostic markers in malignant pleural mesothelioma
4. Markers in diagnosing and follow-up of tuberculosis

Publicații selectate:

* Grigoriu B, Scherpereel A., Screening for malignant mesothelioma--looking for the holy grail., Am J Respir Crit Care Med, 179(9), 2009.

* Vandermeers F, Hubert P, Delvenne P, Mascaux C, Grigoriu B, Burny A, Scherpereel A, Willems L., Valproate, in Combination with Pemetrexed and Cisplatin, Provides Additional Efficacy to the Treatment of Malignant Mesothelioma., Clin Cancer Res, 15, 2009.

* Grigoriu B, Chahine B, Zerimech F, Grégoire M, Balduyck M, Copin MC, Devos P, Lassalle P, Scherpereel A., Serum mesothelin has a higher diagnostic utility than Hyaluronic acid in malignant mesothelioma., Clin Biochem, Mar 17. [Epub ahead of print], 2009.

* Grigoriu BD, Chahine B, Vachani A, Gey T, Conti M, Sterman DH, Marchandise G, Porte H, Albelda SM, Scherpereel A., Kinetics of Soluble Mesothelin in Patients with Malignant Pleural Mesothelioma During Treatment., Am J Respir Crit Care Med., Feb 09 epub (ahead of print), 2009.

* Scherpereel A, Grigoriu BD, Astoul P., Other thoracic cancers. Malignant pleural mesothelioma: biology and diagnosis, Rev Mal Respir., 25(8 Pt 2), 2008.

* Grigoriu BD, Jacobs FM, Mas AE, Prat D, Prévot S, Brivet FG, Disseminated tuberculosis with severe multi- organ failure in a patient with AIDS], Rev Mal Respir, 25(7), 2008.

* Depontieu F, Grigoriu BD, Scherpereel A, Adam E., Delehedde M., Gosset Ph., Lassalle Ph., Loss of Endocan tumorigenic properties after alternative splicing of exon 2, BMC Cancer, 8, 2008.

* Brivet F, Jacobs F, Prat D, Grigoriu B., Sophisticated biomarkers for community-acquired pneumonia severity asessment: gadgets or useful tools?, Intensive Care Medicine, 34, 2008.

* Grigoriu BD, Grégoire M., Chahine B., Scherpereel A, Nouveaux marqueurs diagnostiques du mésothéliome pleural malin, Bull Cancer, 95, 2008.

* Grigoriu BD, Scherpereel A., Diagnostic value of soluble mesothelin in malignant mesothelioma, Thorax, 63, 2008.

* Grigoriu BD, Scherpereel A, Devos P, Chahine B, Letourneux M, Lebailly P, Gregoire M, Porte H, Copin MC, Lassalle P., Utility of osteopontin and serum mesothelin in malignant pleural mesothelioma diagnosis and prognosis assessment, Clinical Cancer Research, 13, 2007.

* Lassalle P, Adam E, Sarrazin S, Depontieu F, Mote V, Villedieu C, Lequien S, Grigoriu B, de Freitas-Carreiras N, Vanpouille C, Delehedde M., Proteoglycans and glycosaminoglycans: Key players in inflammation, Research Signpost, 2006.

* Grigoriu B., Veres L., Mihaescu Tr, Setting probabilities: lost in the Translation, Ann. Int. Med, 116, 1992.

* Scherpereel A., Gentina T., Grigoriu BD., Sénéchal S., Janin A., Tsicopoulos A., Plénat F., Béchard D., Tonnel AB,. Lassalle Ph, Overexpression of Endocan Induces Tumor Formation, Cancer Res, 63, 2003.

* Tonnel A.B., Lelong J., Grigoriu B.D, Chimiokines et récepteurs de chimiokines: futures cibles dans le traitement des maladies allergiques, Revue Francaise d’allergologie et d’immunologie clinique, 44, 2004.

* Cuvelier A, Grigoriu B, Molano LC, Muir JF, Limitations of transcutaneous carbon dioxide measurements for assessing long-term mechanical ventilation, Chest, ; :, 127, 2005.

* Scherpereel A, Depontieu F., Grigoriu BD, Cavestri B, Tsicopoulos A., Gentina T., Jourdain M., Pugin J., Tonnel AB, Lassalle P, Endocan, a new endothelial marker in human sepsis, Critical care medicine, 34(2), 2006.

* Brivet F G. Ducuing S, Jacobs F; Chary I, Pompier R, Prat D, Grigoriu BD, Nordmann P, Accuracy of clinical presentation for differentiating bacterial from viral meningitis in adults. A multivariate approach, Intensive Care Medicine, ,, 31 (12), 2005.

* Grigoriu BD., Jacobs F, Axler O, Prat D, Brivet FG., Capron F, Bronchoalveolar lavage shows lesions of alveolar damage in patients with severe pneumonia, Critical Care, 10, 2006.

* Scherpereel A, Grigoriu BD, Conti M, Gey T, Gregoire M, Copin MC, Devos P, Chahine B, Porte H, Lassalle P, Soluble mesothelin-related protein in the diagnosis of malignant pleural mesothelioma, Am J Respir. Crit Care Med, 173, 2006.

* Brivet FG, Jacobs FM, Colin P., Prat D., Grigoriu B, Cardiac troponin level is not an independent predictor of mortality in septic patients requiring medical intensive care unit admission, Critical Care, 10, 2006.

* Thorette C, Grigoriu B, Canut E, Sobaszek A, Tonnel A, Tillie-Leblond I, Manifestations pulmonaires des prothésistes dentaires, Rev Mal Respir, 23, Suppl 2:, 2006.

* Bogdan-Dragos Grigoriu, Florence Depontieu, Delphine Gourcerol, Patrick Devos, Taoufik Ouatas, Jean-Jacques Lafitte, Marie-Christine Copin, Andre-Bernard Tonnel, Arnaud Scherpereel, Philippe Lassalle, Endocan expression and relationship with survival in human non small cell lung cancer, Clinical Cancer Research, 12, 2006.

* Bogdan Dragos Grigoriu, Ethical flaws in Romania’s health reform, Lancet, 367, 2006.