Ileana Manduteanu

IBPC"N.Simionescu", Bucuresti, .

E-mail: trimite un mesaj.

Nascut(a) in: 1953

Interese: inflamatie, citokine, chemokine, celule vaasculare, atheroscleroza, diabet, boli reumatismale, valve cardiace, vase sanghine, nanotehnologii

Detalii:
Diabetes -induced modifications on Evaluation of
• Sistem cardio-vascular si biologia si patologia valvelor cardiace.
• Carateristici structurale-functionale ale celulelor endoteliale valvulare si modificarile lor in conditii patologice.
• Interactia celulelor endoteliale si celulelor musculare netede cu celulele sangvine.
• Modificarile induse de diabet asupra plachetelor sangvine.
• Rolul moleculelor de adeziune, citokinelor si chemokinelor in patologia vasculara.
• Farmacologie:
o evaluarea efectelor vasculare ale unor medii de contrast folosite in angiografie (polimeri de dextran iodinate),
o efectele medicamentelor anti-inflamatorii asupra celulelor endoteliale: mecanismele implicate,
o folosirea lipozomilor ca transportori pentru tintire specifica de medicamente sau gene.

Details:
-Cardiovascular system and cardiac valves biology and pathology
-Structural and functional characteristics of valvular endothelial cells and their modifications in pathologic conditions
-Endothelial cells-smooth muscle cells interactions with blood cells
-Diabetes-induced modifications on platelets
-The role of cell adhesion molecules, cytokines and chemokines in vascualr pathology
Pharmacology:
-The evaluation of the vascular effects of contrast media used in angiography
- The anti-inflammatory drugs effects on endothelial cells:the mechanisms involved
-The use of liposomes as vectors to specifically target drugs or genes