Lucia Pirvu

National Institute for Chemical-Pharmaceutical Research and Development, Bucharest, .

E-mail: trimite un mesaj.

Nascut(a) in: 1969

Interese: vegetal extracts, pharmacologically active phytocompounds

Details:
1. Research in the field of the obtaining of new, natural medicines/drugs based on the selective
herbal/vegetal extracts, involving both, fundamental research in order to design the most properly phyto-chemical composition, as well as applicative research concerning the following activities: the isolation of the various selective vegetal extracts enriched in the interest phyto-chemical compounds; analytical screening of the obtained vegetal extracts and the selection of the most properly ones by
using specific, combined methods (ex., spectral and spectro-photometrical methods combined with
HPTLC and chemiluminescence methods); the obtaining of the final pharmacological active product with high pharmacological potential by the combination of the most active vegetal extracts; the setting up of the most appropriate and reproducible extractive technologies of these selective extracts and the correspondingly final active product as to the technological transfer from laboratory to pilot level.
2 . Interdisciplinary research coordination (technological, analytical and pharmacological) of a number of 11 national research projects (of PN, CEEX, BIOTECH, ORIZONT, NUCLEU and GRANT type) as project manager (7 projects) or as scientifique responsable of ICCF Partner (4 projects).

Publicații selectate:

* Armatu Alice, Colceru-Mihul Svetlana, Bubueanu Corina, Draghici, Elena, Lucia Pirvu , Evaluation of antioxidant and free scavenging potential of some Lamiaceae species growing in Romania, Romanian Biotechnological Letters (ISI), 15(3), 2010.

* Cornelia Nichita, Neagu Georgeta, Vulturescu Virginia, Lucia Pirvu, Nicoleta Badea, Albulescu Radu, Giurginca Maria, Evaluation of scavenger properties of some flavonoid vegetal extracts obtained from Crataegus monogyna Jacq., Key Engineering Materials (ISI), 415, 2009.

* Alice Armatu, Svetlana Colceru-Mihul, Lucia Pîrvu, Nuta Mănăilă, Maria Ichim, Evaluation of antioxidant and free radical scavenging potential and determination of bioactive compounds of various plant extracts, Proceedings of the International Symposium on New Research in Biotechnology, Series F, 2008.

* Lucia Pîrvu, Alice Armatu, Ileana Rău, Stelian Şchiopu, Dragomir Coprean, Centaurea cyanus L.-herba, chemical composition and therapeutically potential, Proceedings of the International Symposium on New Research in Biotechnology, Series F, 2008.

* Lucia Pîrvu, Alice Armatu, Dragomir Coprean, Contributions to the chemical characterization of some vegetal products with insecticidal activity obtained from Chrysanthemum cinerariafolium L. acclimatized in Constanta, Proceedings of the International Symposium on New Research in Biotechnology, Series F, 2008.

* Viorica Istudor, Cerasela Elena Gird, Ligia Elena DuŃu, Maria Lidia Popescu, Mariana Pavel, Lucia Pirvu, C. Ionescu-Tirgoviste, Preliminary technological studies, laboratory - pilot transfer, fulfilled on an hypoglycaemic natural vegetal product, Fitohipoglic , Annual Congresses of Romanian Medical Association, Resumes, 2008.

* Cornelia Nichita, Cristina Bâzdoacă, Lucia Pîrvu, Maria Giurginca, Aurelia Meghea, Antioxidant capacity of some plant extracts reach in flavones for therapeutically applications, Scientific Bulletin of UPB, Serie B,Chemistry and Materials Science, 67(3), 2005.

* Lucia Pîrvu, Aurelia Meghea, Maria Giurginca, Cristina Bâzdoacă, Cornelia Nichita , Scavenger properties of some natural products with application in the therapy of gastro-intestinal diseases, Scientific Bulletin of UPB, Serie B,Chemistry and Materials Science, 67(3), 2005.

* Viorica Istudor, Mariana Pavel, Cerasela Elena Gîrd, Ligia-Elena Dutu, Lidia-Maria Popescu, Crina Maria Popa, Corina Aramă, Lucia Pîrvu, S. Dima, C. Ionescu-Tîrgovişte , The obtaining technology of the vegetal standardized extract of Phaseoli pericarpium origin and the establishing of the quality control methodology, Acta Diabetologica Romana, 33, 2007.

* Viorica Istudor, Ligia-Elena Dutu, Cerasela Elena Gird, Lidia-Maria Popescu, Mariana Pavel, Corina Arama, Angela Nedelcu, Lucia Pirvu, R. Alexandrescu, C. Ionescu- Tirgoviste, The obtaining technology of the standardized extract of Mori folium origin and the establishing of the quality control methodology, Acta Diabetologica Romana, 33, 2007.

* Cornelia Nichita, Maria Giurginca, Cristina Bazdoaca, Lucia Pirvu, Aurelia Meghea, Vegetal antioxidants obtained from Hypericum perforatum L., Chemistry Magazine, Bucharest (ISI), 58(9), 2007.

* Lucia Pirvu, Cornelia Nichita, Maria Girginca, Aurelia Meghea, Selective plant extracts with application in the therapy of chronic fatigue syndrome, Chemistry Magazine, Bucharest (ISI), 58(9), 2007.

* Lucia Pirvu, Cornelia Nichita, Maria Giuginca, Aurelia Meghea, Structure/antioxidant activity relationship between some natural vegetal polyphenols compounds, Chemistry Magazine, Bucharest (ISI), 57(7), 2006.

* Lucia Pirvu, Armatu Alice, Bubueanu Corina, Pintilie Gabriela, Nita Sultana, Obtaining and chemical characterization of some vegetal acts with corrosion-scaling inhibition properties. Part I. Fagus sylvatica and Alii cepae bulbus extracts, Romanian Biotechnological Letters (ISI), 15(6), 2010.

* Lucia Pirvu, Diana Barbulescu, Cornelia Nichita, Sultana Nita, Svetlana Colceru Mihul, Obtaining and chemical characterization of some vegetal extracts with corrosion-scaling inhibition properties. Part I. Juglandis folium and Agrimoniae herba extracts, Romanian Biotechnological Letters (ISI), 16(1), 2011.

* Lucia Pirvu, Coprean Dragomir, Stelian Schiopu, Svetlana Colceru-Mihul, Vegetal extracts with gastroprotective activity. Part. I. Extracts obtained from Centaurea cyanus L. raw material, Romanian Biotechnological Letters (ISI), Vol.17, No.2, 2012.