Ana-Maria Gurban

Universitatea din Bucuresti, Facultatea de Chimie, Bucuresti, .

E-mail: trimite un mesaj.

Pagina web a instituţiei: http://www.chimie.unibuc.ro

Nascut(a) in: 1974

Interese: chimie, electrochimie, biochimie, chimie analitica, senzori, biosenzori

Detalii:
Domeniile de competenta sunt: chimie analitica si biochimie, electrochimie, senzori si biosenzori, controlul calitatii produselor agro-alimentare si mediului inconjurator.
Experienta in:
- elaborarea de senzori si biosenzori bazati pe enzime din clasa oxido-reductazelor pentru monitorizarea mediului inconjurator si a produselor agro-alimentare.
- dezvoltarea unor noi strategii de imobilizare a enzimelor pe suprafata electrozilor serigrafiati din pasta de carbune, modificati chimic cu mediator redox.
- dezvoltarea unor biosenzori bazati pe nanomateriale de carbon (nanotuburi de carbon) pentru monitorizarea unor estrogeni din mediul inconjurator.
- realizarea de materiale ceramice compozite de tip Al2O3-TiO2 şi Al2O3-TiO2-ZrO2, cu rezistenta mecanica si termica deosebita, cu aplicatii posibile in obtinerea unor suporti pentru dezvoltarea de biosenzori.
Activitatile curente implica dezvoltarea de senzori si biosenzori bazati pe enzime din clasa oxido-reductazelor pentru monitorizarea compusilor estrogeni, fungicidelor ditiocarbamate, a mediului si a produselor agro-alimentare, dezvoltarea de noi strategii pentru imobilizarea enzimelor pe suprafata electrozilor serigrafiati, chimic modificati cu mediatori redocsi si materiale nanocompozite, precum si caracterizarea electrochimica a acestora.

Details:
Competence areas are: analytical chemistry and biochemistry, electrochemistry, sensors and biosensors, quality control of agro-food products and environment.
Experience in:- development of sensors and biosensors based on enzymes from oxido-reductase class for environment and agro-food products monitoring.
- development of new strategies for immobilising enzymes on the carbon paste screen-printed electrodes surface, chemically modified with appropriate redox mediators.
- development of biosensors based on carbon nanomaterials (carbon nanotubes) for estrogens monitoring from environment.
- realisation of ceramic composite materials, type Al2O3-TiO2 şi Al2O3-TiO2-ZrO2, with special thermal and mechanical resistance, with potential applications in obtaining supports for the development of biosensors.
My current activities involve the development of sensors and biosensors based on enzymes from oxido-reductase class for monitoring of estrogenic compounds, dithiocarbamate fungicides, environmental and agro-food products, the development of new strategies for immobilising enzymes on the screen-printed electrodes surface, chemically modified with appropriate redox mediators and nanocomposite materials and also the electrochemical characterisation of the modified sensors and biosensors.
Disposable biosensors based on aldehyde dehydrogenase were used for metham-sodium and methyl isothiocyanate fungicides determination, while biosensors based on L-malate dehydrogenase (L-MDH), NADH oxidase and malate quinon oxidoreductase enzymes were used for determination of L-malic acid and monitoring of wine malolactic fermentation. The developed devices in different configurations have been used for the analysis of real samples of French and Romanian wines, and they were also tested for monitoring of L-malic acid during an artificial fermentation process, simulated in Bochum University (Germany). In the last period I was able to approach a new scientific field, namely that of nanomaterials, and so it was possible to developed new systems of biosensors rely on carbon nanotubes and screen-printed electrodes, for determination of xenoestrogenic compounds and tumor biomarkers.
Working and collaborating with researchers from the Metallurgical Research Institute from Bucharest, we managed to obtain ceramic composit materials, as Al2O3-TiO2 and Al2O3-TiO2-ZrO2, with special mechanical and thermal resistance. There have been performed scientific studies on superalumina refractory and advanced ceramic products.
My participation in various national and international congresses helped me to interact with other researchers in the field, and gave me the possibility of developing new scientific ideas and of new systems of biosensors for detection of metabolites of major importance, for monitoring the quality of life, food and environment.

Publicații selectate:

* Thierry Noguer, Ana-Maria Balasoiu, Alina Avramescu & Jean-Louis Marty, Development of a disposable biosensor for the detection of metham sodium and its metabolite MITC, Analytical Letters, 34(4), 2001.

* Bogdan Bucur, Elena Mallat, Ana-Maria Gurban, Yana Gocheva, Carine Velasco, Jean-Louis Marty, Thierry Noguer, Strategies to develop malic acid biosensors based on malate quinone oxidoreductase (MQO), Biosensors and Bioelectronics, 21(12), 2006.

* Ana-Maria Gurban, Thierry Noguer, Camelia Bala, Lucian Rotariu, Improvement of NADH detection using Prussian blue modified screen-printed electrodes and different strategies of immobilisation , Sensors and Actuators B:Chemical, 128(2), 2008.

* Ana-Maria Gurban, Lucian Rotariu, Mihaela Baibarac, Ioan Baltog, Camelia Bala, Sensitive detection of endocrine disrupters using ionic liquid – Single walled carbon nanotubes modified screen-printed based biosensors , Talanta, 85 (4), 2011.

* Adina Arvinte, Lucian Rotariu, Camelia Bala, Ana Maria Gurban, Synergistic effect of mediator–carbon nanotube composites for dehydrogenases and peroxidases based biosensors , Bioelectrochemistry, 76(1-2), 2009.