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Free Radicals Detection by ESR PBN Spin-Trap Technique

Domenii publicaţii > Fizica + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: Grigore Damian, Dina Petrisor, Vasile Miclaus

Editorial: INOE&INFM, Journal of Optoelectronics and Advanced Materials, 9(4), p.1010-1013, 2007.


The formation and reaction of hydroxyl radicals in gamma-irradiated Metoclopramide (4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy benzamide monohydrochloride monohydrate ) and complex Fenton reaction was studied by Electron Spin Resonance spectroscopy (ESR). Specific radicals derived from purely chemical structures and reactions were detected using N-t-Butyl- α-phenylnitrone (PBN) as spin trap. Some spectroscopic properties and suggestions concerning possible nature of the radicals are discussed

Cuvinte cheie: radicali liberi, capcane de spin, PBN, ESR, Metoclopramid, reactie Fenton // free radicals, spin trap, PBN, ESR, Metoclopramide, Fenton reaction