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Synthesis and characterisation of core-shell structures for orthopaedic surgery

Domenii publicaţii > Stiinte ingineresti + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: Edina Rusen, Cãtãlin Zaharia, Teodora Zecheru, Bogdan Mãrculescu, Robert Filmon, Daniel Chappard, Roxana Bãdulescu, Corneliu Cincu

Editorial: Elsevier, Journal of Biomechanics, 40, p.3349-3353, 2007.

Rezumat:

This paperwork deals with the obtaining and characterisation of new acrylic cements for bone surgery. The final mixture of cement contains derivatives of methacryloyloxyethyl phosphate, methacrylic acid and 2-acrylamido-2-methyl-1-propane sulphonic acid. The idea of using these monomers is sustained by their ability to form ionic bonds with barium, which is responsible for X-ray reflection and biocompatibility of the polymers derived from these structures.
The strategy consists in the obtaining of core-shell structures through heterogeneous polymerisation, structures used for the manufacture of the final cement. The orthopaedic cements were characterised by compression resistance and cytotoxicity assays.

Cuvinte cheie: bone cement; radio-opacity; mechanical properties; cytotoxicity assays