Functionalized Polyvinyl Alcohol Derivatives Thin Films for Controlled Drug Release and Targeting Systems: MAPLE Deposition and Morphological, Chemical and In Vitro Characterization
We report thin film deposition of polyvinyl alcohol functionalized with carboxylic groups bound to aromatic nucleus (PVACOOH) by matrix-assisted pulsed laser evaporation (MAPLE). We used a KrF* excimer laser source (l = 248 nm, t = 25 ns, n ¼ 5 Hz). The obtained thin films have been investigated by FTIR, AFM, and in vitro tests. We identified the best compromise between the parameters of laser processing and characteristics of nanostructured thin
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