Ethical implications of communicating molecular test results to families with hereditary predispositionto cancer
Hereditary predisposition to breast and ovarian cancer is mainly attributable to tumor suppressor genes BRCA1 and BRCA2. Together, these two genes account for up to 80% of cancer cases in hereditary breast and ovarian cancer (HBOC) families. Molecular diagnosis is nowadays standard practice in western world and allows medical oncogenetic follow-up for BRCA mutation carriers and for their families. Close surveillance of patients includes early and
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