Gabriel Balmus

My specific research interest is the study of DNA damage response and its correlation to human disease.

Gurdon Institute, University of Cambridge, Cambridge, .

E-mail: trimite un mesaj.

Pagina web a instituţiei: http://www.gurdon.cam.ac.uk/
Pagina web personala: http://www.gurdon.cam.ac.uk/~jacksonlab/

Nascut(a) in: 1980

Interese: repararea ADN, cancer

Publicații selectate:

* Balmus G, Barros AC, Wijnhoven PWG, Lescale C, Hasse HL, Boroviak K, et al., Synthetic lethality between PAXX and XLF in mammalian development., Genes and Development, 30, 2016.

* McIntyre RE, Nicod J, Robles-Espinoza CD, Maciejowski J, Cai N, Hill J, Verstraten R, Iyer V, Rust AG, Balmus G, Mott R, Flint J, Adams DJ, A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice., G3, 6, 2016.

* Lescale C, Hasse HL, Blackford AN, Balmus G, Bianchi JJ, Yu W, et al.(, Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination., Cell Reports, 16 (11), 2016.

* Subbaramaiah K, Brown KA, Zahid H, Balmus G, Weiss RS, Herbert B, Dannenberg AJ, Hsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells., The Journal of Biological Chemistry, 291, 2016.

* G Balmus, PX Lim, A Oswald, KR Hume, A Cassano, J Pierre, A Hill, W Huang, A August, T Stokol, T Southard, RS Weiss, HUS1 regulates in vivo responses to genotoxic chemotherapies, Oncogene, 2015.

* Gabriel Balmus, Natasha A Karp, Bee Ling Ng, Stephen P Jackson, David J Adams, Rebecca E McIntyre, A high-throughput in vivo micronucleus assay for genome instability screening in mice, Nature Protocols, 10(1), 2015.

* Sachiyo Okayama, Levy Kopelovich, Gabriel Balmus, Robert S Weiss, Brittney-Shea Herbert, Andrew J Dannenberg, Kotha Subbaramaiah, p53 Protein Regulates Hsp90 ATPase Activity and Thereby Wnt Signaling by Modulating Aha1 Expression, Journal of Biological Chemistry, 289(10), 2014.

* Gabriel Balmus, Rebecca E McIntyre, Genetic screens in mice for genome integrity maintenance and cancer predisposition, Current opinion in genetics & development, 24, 2014.

* Balmus G, Zhu M, Mukherjee S, Lyndaker AM, Hume KR, Lee J, Riccio ML, Reeves AP, Sutter N, Noden DM, Peters RM, Weiss RS., Disease severity in a mouse model of Ataxia Telangiectasia is modulated by the DNA damage checkpoint gene Hus1., Human Molecular Genetics, 21, 2012.

* Erin K. Daugherity, Gabriel Balmus, Ahmed Al Saei, Elizabeth Moore, Delbert Abi Abdallah, Arlin B. Rogers, Robert S. Weiss and Kirk J. Maurer, The DNA damage checkpoint protein ATM promotes hepatocellular apoptosis and fibrosis in a mouse model of non-alcoholic fatty liver disease, Cell cycle, 11(10), 2012.

* Q Qi, W Huang, Y Bai, G Balmus, RS Weiss, A August , A Unique Role for ITK in Survival of Invariant NKT Cells Associated with the p53-Dependent Pathway in Mice, The Journal of Immunology, 188(8), 2012.

* Holloway J.K., Mohan S., Balmus G., et al., Mammalian BTBD12 (SLX4) localizes to meiotic chromosome cores and is essential for normal spermatogenesis, PLoS Genet., 7(6), 2011.

* Jinadasa R., Balmus G., Gerwitz L., et al. , Derivation of Thymic Lymphoma T-cell Lines from Atm-/- and p53-/- Mice, J Vis Exp., 3 (50), 2011.

* Gabriel Balmus, Vladimir A. Trifonov., Larisa S. Biltueva, Patricia C.M. O'Brien, Elena S. Alkalaeva, Beiyuan Fu, Julian A. Skidmore, Twink Allen, Alexander S. Graphodatsky, Fengtang Yang & Malcolm A. Ferguson-Smith, Cross-species chromosome painting among camel, cattle, pig and human:further insights into the putative Cetartiodactyla ancestral karyotype, Chromosome Research, 15, 2007.

* D. Di Berardino, G. Balmus, D. Nicodemo, G. Coppola, C. Verdovila, G. Coppola, G. Ene, G. Bozzini, G. Di Meo and L.Ianuzzi, Cytogenetic characterization of metaphase chromosomesof alpaca (Lama pacos): I-GTG/RBG-banded karyotypes and ideograms, Chromosome Research, 12 supp 1, 2004.

* Basset, P, Yannic, G, Yang, FT, O'Brien, PCM, Graphodatsky, AS, Ferguson-Smith, MA, Balmus, G, Volobouev, VT, Hausser, J, Chromosome localization of microsatellite markers in the shrews of the Sorex araneus group., Chromosome Research, 14(3), 2006.

* Di Berardino, D, Nicodemo, D, Coppola, G, King, AW, Ramunno, L, Cosenza, GF, Iannuzzi, L, Di Meo, GP, Balmus, G, Rubes, J, Cytogenetic characterization of alpaca (Lama pacos, fam. Camelidae) prometaphase chromosomes, Cytogetetics and Genome Research, 115 (2), 2006.