Inscriere cercetatori

Asociatia Ad Astra a cercetatorilor romani lanseaza BAZA DE DATE A CERCETATORILOR ROMANI DIN DIASPORA. Scopul acestei baze de date este aceea de a stimula colaborarea dintre cercetatorii romani de peste hotare dar si cu cercetatorii din Romania. Cercetatorii care doresc sa fie nominalizati in aceasta baza de date sunt rugati sa trimita un email la cristian.presura@gmail.com

Syntheses of 2-Alkylamino- and 2-Dialkylamino-4,6-diarylpyridines and 2,4,6-Trisubstituted Pyrimidines Using Solid-Phase-Bound Chalcones

Domenii publicaţii > Chimie + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: Katritzky, Alan R.; Serdyuk, Larisa; Chassaing, Christophe; Toader, Dorin; Wang, Xiaojing; Forood, Behrouz; Flatt, Brenton; Sun, Congcong; Vo, Kim

Editorial: J. Comb. Chem., 2(2), p.182-185, 2000.

Rezumat:

Several substituted 2- and 4-hydroxyacetophenones are linked to Wang resin via a modified Mitsunobu protocol. These resin-bound acetophenones are condensed with arom. aldehydes, and the resulting chalcones are used for the synthesis of 2-dialkylamino- and 2-alkylamino-4,6-diarylpyridines, and 2-alkyl-4,6-diaryl- and 2,4,6-triarylpyrimidines in a manner suitable for combinatorial applications

Cuvinte cheie: combinatorial chemistry, solid phase synthesis