Autori: T. Marcovici, I. Sabau, I. Simedrea, M. Puiu, E. Gamaniuc;

Editorial: nature publishing group, European journal of human genetics, Volume 14 Supplement 1 May 2006, p.146, 2006.

Rezumat:

Mongolian spot is a hereditary developmental condition caused by
entrapment of melanocytes in the dermis during their migration from
the neural crest into the epidermis. A child may have one or several on
the lower back They are more common in dark-skinned infants and,
in some cases, involve unusual sites. Nevus of Ota is a permanent
unilateral congenital/aquired blue/gray patch on the face and it may
involve the ocular surface.
We present a five-months old dark-skinned female admitted in our clinic
for pneumonia and seizures. She is the third child of an young healthy
couple. The pregnancy was not followed up and she was delivered
full term, with a weight of 3880 g and Apgar score 9. Girl’s growth and
development were normal.
By clinical examination we noticed multiple bluish spots involving large
skin areas: the right side of the face, shoulders, back, presacral area and
buttocks. Right eye’s bulbar conjunctiva was also involved. The patchs
and eye hyperpigmentation are congenital and they have not changed
since birth. Ophtalmologic examination identified melanocytosis of the
entire uveal tract and normal intraocular pressure. MRI of the brain
was normal.
Conclusions: There is a moderate case of nevus of Ota with
ocular melanosis. Ophtalmologic and dermatologic follow-up care is
necessary.

Cuvinte cheie: nevul Ota, pete mongoloide, hiperpigmentare oculara // Nevus of Ota, Mongolian spots, eye hyperpigmentation

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