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Reaction time and implicit learning in multiple episode schizophrenia patients

Domenii publicaţii > Ştiinţe medicale + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: Coman H, Nemeș B, Nica S, Rusu I, Herța D, Cosman D

Editorial: Journal of Cognitive and Behavioral Psychotherapies, 10(2), p.147-160, 2010.


Cognitive impairment in schizophrenia involves multiple cognitive functions, especially memory, attention, motor skills, executive functions and intelligence.
Our study set out to outline and assess impairments of executive functions in multiple episode schizophrenia patients, especially reaction times, response selection and implicit learning.
The study included 39 patients diagnosed with schizophrenia according to DSM-IV-TR criteria, with at least one prior psychotic episode, and 30 controls with no family or personal history of psychiatric disorder. Both groups were assessed through the Set Shifting Test and the Go-No-Go Test on a Cogtest Console (Cogtest, Inc.).
Cognitive assessment through Set Shifting Test revealed that implicit learning, understood as a decrease of reaction times to sequences of stimuli, occurs to a similar extent in multiple episode schizophrenia patients and in controls; however, implicit learning leads to a significantly higher number of erroneous responses in schizophrenia patients. The Go-No-Go Test revealed an augmentation of reaction times in studied patients when the task involved selection between the execution and non-execution of a response. Moreover, schizophrenia patients recorded a significantly higher rate of errors whenever non-execution of response was the correct response for the task.

Cuvinte cheie: multiple episode schizophrenia, executive functions, SST, Go-No-Go, implicit learning, reaction time, inhibition of response