Scopul nostru este sprijinirea şi promovarea cercetării ştiinţifice şi facilitarea comunicării între cercetătorii români din întreaga lume.
Autori: Mehmet Ates, Veysel Demir, Zikri Arslan, James Daniels, Ibrahim O. Farah, Corneliu Bogatu
Editorial: Paul B. Tchounwou, John Wiley & Sons, Inc, Environmental Toxicology, 30, p.109-118, 2015.
In this study, Artemia salina (crustacean filter feeders) larvae were used as a test model to
investigate the toxicity of aluminum oxide nanoparticles (Al2O3 NPs) on marine microorganisms. The
uptake, toxicity, and elimination of alpha-Al2O3 (50 nm and 3.5 μm) and gamma-Al2O3 (5 nm and 0.4 μm) NPs were studied. Twenty-four and ninety-six hour exposures of different concentrations of Al2O3 NPs to Artemia larvae were conducted in a seawater medium. When suspended in water, Al2O3 NPs aggregated substantially with the sizes ranging from 6.3 nm to > 0.3 μm for spherical NPs and from 250 to 756 nm for rod shaped NPs. The phase contrast microscope images showed that NPs deposited inside the guts as aggregates. Inductively coupled plasma mass spectrometry analysis showed that large particles (3.5 μm alpha-Al2O3) were not taken up by Artemia, whereas fine NPs (0.4 μm gamma-Al2O3) and ultra-fine NPs (5 nm gamma-Al2O3 and 50 nm alpha-Al2O3) accumulated substantially. Differences in toxicity were detected as changing with NP size and morphology. The malondialdehyde levels indicated that smaller gamma-Al2O3 (5 nm) NPs were more toxic than larger gamma -Al2O3 (0.4 μm) particulates in 96 h. The highest mortality was measured as 34% in 96 h for gamma-Al2O3 NPs (5 nm) at 100 mg/L (LC50>100 mg/L). Gamma -Al2O3 NPs were more toxic than alpha-Al2O3
NPs at all conditions.
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