Clinico-pathological correlations in fatal ischemic stroke. An immunohistochemical study of human brain penumbra
Ischemic stroke is one of the most frequent pathologies with high invalidating potential and a leading cause of death. The brain tissue adjacent to the central necrotic core, defined as penumbra, was extensively characterized mostly by imaging techniques and in animal models. Our goal was to identify a large panel of molecules in this particular area on human brains harvested at autopsy. 21 patients with ischemic stroke and 7 control cases were taken
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