Autori: Gh. Mateescu, T. Craciunescu

Editorial: Editura Horia Hulubei, Bucuresti, 2000.

Rezumat:

„An image worth more than a thousand words” – this is the thought that underlie this vision on the field of nuclear medicine. It starts with a review of some theoretical and engineerical that grounds the field of nuclear medicine: nuclear radiation, interaction of radiation with matter, radiation detection and measurement, numerical analysis. Products and methods needed for the implementation of diagnostic and research procedures in nuclear medicine are presented: radioisotopes and radio-pharmaceuticals, equipment for in-vitro (radio-immuno-assay, liquid scintillation counting) and in-vivo investigations (thyroid uptake, renography, dynamic studies, imaging). A special attention is focused on medical imaging theory and practice as a source of clinical information (morphological and functional). The large variety of parameters, components, biological structures and specific properties of live matter determines the practical use three-dimensional tomographic techniques based on diverse physical principles: single-photon emission, positron emission, X-rays transmission, nuclear magnetic resonance, ultrasounds transmission and reflection, electrical impedance measurement. The fundamentals reconstruction algorithms (algorithms based on the projection theorem and Fourier filtering, algebraical reconstruction techniques, algorithms based on statistical principles: maximum entropy, maximum likelihood, Monte Carlo algorithms) are depicted in details. A method based on the use of the measured point spread function is suggested. Some classical but often used techniques like linear scintigraphy and Anger gammacamera imaging are also presented together with some image enhancement techniques like Wiener filtering, blind deconvolution. The topic of the book is illustrated with some clinical samples obtained with nuclear medicine devices developed in the nuclear medicine laboratory of the National Institute of Nuclear Physics and Engineering in Bucharest.

Cuvinte cheie: nuclear medicine