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Selective Separation of Penicillin V from Phenoxyacetic Acid Using Liquid Membranes

Domenii publicaţii > Stiinte ingineresti + Tipuri publicaţii > Articol în revistã ştiinţificã

Autori: Dan Cascaval, Corneliu Oniscu, Coca Cascaval

Editorial: Biochemical Engineering Journal, 5, p.45-50, 2000.

Rezumat:

The selective separation of Penicillin V from phenoxyacetic acid using extraction and transport through liquid membranes consisting of
1,2-dichloroethane and Amberlite LA-2 as carrier was studied. The selective separation is the result of the difference between the acidity
and hydrophobicity of the two compounds.
The experimental data indicated the decisive in¯uences of pH (difference between the feed and stripping phases), carrier concentration in
solvent phase (0±80 g/l Amberlite LA-2) and mixing intensity. Thus, the selectivity factor, de®ned as the ratio between the ®nal mass ¯ows
of Penicillin V and phenoxyacetic acid, was enhancing by reducing the pH gradient between the aqueous solutions and by using low
concentrations of carrier inside the liquid membrane, in the conditions of high stirrers rotation speed values. The selectivity factor value
varied between 2.5 and 80.4.

Cuvinte cheie: Pertraction, Liquid membranes, Reactive extraction, Bioseparation