Articolele autorului Radu Silaghi-Dumitrescu
Link la profilul stiintific al lui Radu Silaghi-Dumitrescu

Ferryl haem protonation gates peroxidatic reactivity in globins

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Reaction of Aplysia limacina metmyoglobin with hydrogen peroxide

Myoglobin (Mb) from gastropod mollusc Aplysia limacina shows only 20% sequence homology to the 'prototype' sperm whale Mb but exhibits a typical Mb fold and can reversibly bind oxygen. An intriguing feature of aplysia Mb is that it lacks the distal histidine and displays a ligand stabilisation based on an arginine. Here we report the reaction of aplysia metMb with hydrogen peroxide studied by optical and electron paramagnetic resonance (EPR) spectroscopies.

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Structure/function correlations in binuclear non-heme ferrous sites: Specific characterization of the active sites in m-Ferritin and nitric oxide reductases

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Computational study of the non-heme iron active site in superoxide reductase and its reaction with superoxide

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A flavodiiron protein and high molecular weight rubredoxin from Moorella thermoacetica with nitric oxide reductase activity

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Nitric oxide reduction by heme-thiolate enzymes (P450nor): A reevaluation of the mechanism

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A non-heme iron nitric oxide reductase that protects against nitrosative stress in acetogenic bacteria

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How microbes detoxify superoxide, hydrogen peroxide and nitric oxide. The non-heme iron reductive paradigm

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Hemes revisited by density functional approaches. 1. The axial ligand and the dioxygen-peroxo chemistry

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Heme ferrous-hydroperoxo complexes: some theoretical considerations

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