Scopul nostru este sprijinirea şi promovarea cercetării ştiinţifice şi facilitarea comunicării între cercetătorii români din întreaga lume.
The properties of copolymers (physical, chemical, biocompatibility, etc.) depend on their chemical structure and micro structural characteristics. We have prepared radio-opaque polymers based on the copolymers of methyl methacrylate (MMA) and 2-[2',3',5'-triiodobenzoyl]oxoethyl methacrylate (TIBOM). The copolymerization reaction between TIBOM and MMA showed that the reactivity ratios were r1= 0.00029 and r2=1.2146. The composition diagram is typical
Read moreAcrylic cement was introduced into practice by Sir John Charnley 40 years ago. The advantages of this cement are the good and durable fixation of the hip and knee prostheses ensuring the distribution of the forces from the implant to the bone. It is also used in vertebroplasties, osteoporosis and bone substitutes. One of the major problems associated with the use of bone cements is the decrease of the mechanical properties in time due to the incompatibility
Read moreThis paperwork deals with the obtaining of a new radio-opaque biomaterial that can be used in the manufacture of bone or dental cements. We have obtained some radio-opaque copolymers based on methyl methacrylate (MMA) and 2-iodothiophene (ITf). The copolymers were characterised by Gel Permeation Chromatography and their molecular weights were obtained. Next, they were subjected to viscosity analysis to evaluate the K and α constants from Kuhn-Mark-Houwink-Sakurada
Read moreWe present in this work another possible application of p(2-hydroxyethyl methacrylate-co-methacryloyloxyethyl phosphate), as drug delivery system. In this respect, we synthesised p(HEMA-co-MOEP) microbeads that were characterised by SEM, FTIR, elemental analysis, swelling rate, flow cytometry and were submitted to cytotoxicity assays
Read moreThe purpose of using polymers in drug delivery systems is to be able to create a membrane-like barrier that would control the delivery of the active agent for an extended period. Poly (2-hydroxyethyl methacrylate) (pHEMA), when cross-linked, swells to a significant extent. Hence, it was thought necessary to determine its degree of swelling when incorporating methyl methacrylate (MMA), which is a hydrophobic monomer. The polymeric micro-beads of p(HEMA)
Read moreThe purpose of using polymers in drug delivery systems is to be able to create a membrane-like barrier that would control the delivery of the active agent for an extended period. Poly(2-hydroxyethyl methacrylate) (pHEMA), when cross-linked, swells to a significant extent. Hence, it was thought necessary to determine its degree of swelling when incorporating methyl methacrylate (MMA), which is a hydrophobic monomer. The polymeric micro-beads of p(HEMA)
Read moreWithin the last few years, there have been made investigations to find macromolecular systems with chemical functions to induce hydroxyl-apatite (HA) formation both in vitro and in vivo. In this respect, we prepared some copolymers of 2-hydroxyethyl methacrylate and 2-methacryloylamido-glutamic acid and we evaluated their capacity to initiate the formation and growth of HA crystals on surface when incubated in physiological fluids. SEM analysis showed
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