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Publicatii proprii
Alternative splicing results in RET isoforms with distinct trafficking properties
RET encodes a receptor tyrosine kinase that is essential for spermatogenesis, development of the sensory, sympathetic, parasympathetic, and enteric nervous systems and the kidneys, as well as for maintenance of adult midbrain dopaminergic neurons. RET is alternatively spliced to encode multiple isoforms that differ in their C-terminal amino acids. The RET9 and RET51 isoforms display unique levels of autophosphorylation and have differential interactions
Read moreGiant magnetocaloric effect in Tm-based bulk metallic glasses
We report that the maximum magnetic entropy change ΔSm of Tm39Ho16Co20Al25 metallic glass can reach 18.3 Jkg−1K−1 under 5 T, which is larger than that of any previously reported metallic glasses and comparable with that of the giant magnetocaloric effect material Gd5Si2Ge2 compound. Even under low magnetic fieldof2 T, the ΔSm of the glass can reach 10.3 Jkg−1K−1 which is even larger that of most of other metallic glasses under 5 T. The
Read moreSpectroscopic investigation of P2O5-CdO-Li2O glass system
A systematic IR, Raman and ESR study of the P2O5-CdO-Li2O glass system--a possible dosimeter material, is reported. The proportion of P2O5 remains constant at 0.5 mol% and those of CdO and Li2O are changed from 0 to 0.5 mol%. IR and Raman spectra allowed us to identify the structural units which appear in the structural network of these phosphate glasses and also the network modifier role of Cd2+ and Li+ ions. Generally, a local network structure
Read moreDesigning thermotropic liquid crystalline polyazomethines based on fluorene and/or oxadiazole chromophores
The main objective of this paper was to synthesize luminescent thermotropic liquid crystalline polyazomethines containing chromophoric mesogen, which design has been addressed to optoelectronic materials. The investigation of the thermotropic behavior by three complementary methods of analyses, i.e. polarized optical microscopy, differential scanning calorimetry and wide angle X-ray diffraction, indicated a nematic mesophase for the polymers containing
Read moreImino-chitosan biodynamers
The imine-bond formation on chitosan backbones occurs with very low yields in aqueous solutions and is significantly improved in hydrogels or in solid state films. The dynamic exchanges of imino-R groups and colour transfer can occur at the interfaces between various hydrogels and solid state films.
Read moreEffects of periodicity perturbations on the transmission by underwater phononic crystals
The effects of periodicity perturbations in underwater phononic crystal layers composed of nonin- terpenetrating rows of identical shells are investigated. The results for one row are obtained by using a multiple scattering method between shells. Then, taking into account the multiple reflections and transmissions between two adjacent rows, a Debye series method is used to calculate the reflection and transmission coefficients by a finite number
Read moreMolecular mechanisms of RET receptor-mediated oncogenesis in multiple endocrine neoplasia 2
Multiple endocrine neoplasia type 2 is an inherited cancer syndrome characterized by tumors of thyroid and adrenal tissues. Germline mutations of the REarranged during Transfection (RET) proto-oncogene, leading to its unregulated activation, are the underlying cause of this disease. Multiple endocrine neoplasia type 2 has been a model in clinical cancer genetics, demonstrating how knowledge of the genetic basis can shape the diagnosis and treatment
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