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Publicatii proprii
Effects of Volatile Emissions of Picea abies Fresh Debris on Ips duplicatus Response to Characteristic Synthetic Pheromone
Ips duplicatus is an important pest of Norway spruce (Picea abies) planted outside of its natural range. This species uses olfactory signals to identify the spruce trees favourable for colonisation. The knowledge of the beetles' response to these stimuli is important for managing this pest. Therefore, the response of Ips duplicatus to a specific synthetic pheromone was investigated under some natural sources of volatile emissions characteristic of
Read moreThe migrationist phenomenon in the context of the current economic and financial crisis. Comparative analyses
The crisis of the global financial markets that struck the world economy in the mid 2008 affected the world economy as a whole; nevertheless, it also had a great impact upon the labour force market in the European countries. The migration dropped, differentiated by certain geographic areas. This work proposes an analysis of the migration phenomenon under the economic and financial crisis impact in certain countries of the European Union over the
Read moreHyperhomocysteinemia in moderate and severe hypothyroidism
The aim of the study was to evaluate prevalence of hyerhomocysteinemia in hypothyroid patients and the effect of folic acid supplementation when serum homocysteine was over risk level . Subjects with moderate(Group1) and severe hypothyroidism(Group2) were evaluated before any therapy and after 6 months of combined folic acid with levothyroxine substitution. Homocysteine (Hcy), folic acid, thyroid hormones, lipids were measured for all subjects. Thyroglobulin,
Read moreInsulin-like growth factor-I correlates more closely than growth hormone with insulin resistance and glucose intolerance in patients with acromegaly.
In normal subjects growth hormone (GH) and insulin-like growth factor-I (IGF-I) have opposing effects on glucose metabolism. Active acromegaly is associated with insulin resistance (IR) and glucose intolerance although both GH and IGF-I are elevated. Our objective was to compare whether GH or IGF-I correlates more closely with IR and glucose intolerance in acromegaly. Basal serum IGF-I and GH, glucose and insulin during an oral glucose tolerance
Read moreMethylglyoxal modification of Na(v)1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy
This study establishes a mechanism for metabolic hyperalgesia based on the glycolytic metabolite methylglyoxal. We found that concentrations of plasma methylglyoxal above 600 nM discriminate between diabetes-affected individuals with pain and those without pain. Methylglyoxal depolarizes sensory neurons and induces post-translational modifications of the voltage-gated sodium channel Na(v)1.8, which are associated with increased electrical excitability
Read moreThe evolution of the Sarmatian palaeoclimate in North-Eastern Romania:A palaeobotanical approach
In the present paper, 24 palaeobotanical assemblages were analysed and, by applying the Coexistence Approach method, the MAT (Mean Annual Temperature), MAP (Mean Annual Precipitations), CMT (Coldest Month Mean Temperature) and WMT (Warmest Month Mean Temperature) were calculated for the Sarmatian deposits from the north-east of Romania. The values calculated for the climatic parameters were used to obtain palaeoclimatic maps with their distribution
Read moreDisease severity in a mouse model of Ataxia Telangiectasia is modulated by the DNA damage checkpoint gene Hus1.
The human genomic instability syndrome Ataxia Telangiectasia (A-T), caused by mutations in the gene encoding the DNA damage checkpoint kinase ATM, is characterized by multisystem defects including neurodegeneration, immunodeficiency, and increased cancer predisposition. ATM is central to a pathway that responds to double strand DNA breaks, while the related kinase ATR leads a parallel signaling cascade that is activated by replication stress. To
Read moreSemantic Subtyping with an SMT Solver
We study a first-order functional language with the novel combination of the ideas of refinement type (the subset of a type to satisfy a Boolean expression) and type-test (a Boolean expression testing whether a value belongs to a type). Our core calculus can express a rich variety of typing idioms; for example, intersection, union, negation, singleton, nullable, variant, and algebraic types are all derivable. We formulate a semantics in which expressions
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