Articolele autorului Mugurel Constantin Rusu
Link la profilul stiintific al lui Mugurel Constantin Rusu

Telocytes form networks in normal cardiac tissues

Telocytes (TC) are a class of interstitial cells present in heart. Their characteristic feature is the presence of extremely long and thin prolongations (called telopodes). Therefore, we were interested to see whether or not TCs form networks in normal cardiac tissues, as previously suggested. Autopsy samples of cardiac tissues were obtained from 13 young human cadavers, without identifiable cardiac pathology and with a negative personal history

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Quantitative and qualitative bone analysis in the maxillary lateral region

PURPOSES: The present study was conducted to assess the amount of bone present between root apices and the maxillary sinus floor in the maxillary lateral region, to compare the evaluations on cone beam computed tomography (CBCT) and orthopantomography (OPG), and to evaluate the bone density of the same region using three-dimensional images on CBCT. METHODS: Fifty-one dental patients were recruited for the study. All subjects were partially edentulous.

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Skin telocytes

A distinctive stromal cell-type, the telocyte (TC), has recently been described to send specific long prolongations (telopodes) alternating thin segments (podomers) with dilations (podoms). Even though one would expect TCs to be identified in various stromal tissues, there were not yet reported evidence of skin TCs. We aimed to check for the presence of TCs in human skin dermis. Transmission electron microscopy revealed the presence in dermis of

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Telocytes in Parotid Glands

The parotid histological structure includes acinar, ductal, and myoepithelial cells, surrounded by a connective stromal component. The parotid stroma is mostly regarded as an inert shell, consisting of septa, which divide the parenchyma. Telocytes were recently identified as a new stromal cell type in various organs, including exocrine pancreas. We aimed to evaluate telocytes presence in parotid stroma and whether their topographical features might

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Tracheal telocytes

Recently, a novel type of stromal cell - the telocytes (TC) - was identified in mouse trachea. These cells are known to possess the ultrastructural characteristics which support their role in intercellular signaling. We found TC in all stromal compartments of the tracheal wall. TC with long prolongations(telopodes, Tp) were lining longitudinally the collagen bundles, and were serially arranged (end-to-end connections of Tp were found). Noteworthy,

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The extramandibular inferior alveolar nerve in cases with severely atrophic lower jaws.

There are very few evidences on the extramandibular course (EMC) of the inferior alveolar nerve (IAN). We report here two such cases. The first one was encountered at dissection, in a human adult female cadaver where the right IAN terminal division was identified in the premolar region, above a severely atrophied mandibular body. The second case was a patient evaluated by cone-beam CT, who presented with an extremely atrophic mandible with bilateral

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The human trigeminal ganglion: c-kit positive neurons and interstitial cells.

OBJECTIVES: The presence of c-kit positive neurons in sensory ganglia has been verified in various species but not in humans. Our aim has been to identify whether human primary trigeminal neurons label with c-kit/CD117 and thus, whether data gathered in animal studies can be extrapolated to humans. We also intended to establish whether, and which non-neuronal cells also label with c-kit in the trigeminal ganglion. METHODS: Human adult trigeminal

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Extrahepatic and Intrahepatic Human Portal Interstitial Cajal Cells

Portal interstitial cells of Cajal (PICCs), acting as vascular pacemakers, were previously only identified in nonhumans. Moreover, there is no evidence available about the presence of such cells within the liver. The objective of the study is to evaluate whether or not PICCs are identifiable in humans and, if they are, whether or not they are following the scaffold of portal vein (PV) branches within the liver. We obtained extrahepatic PVs and liver

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Morphologic features of the fetal mandibular condyle: layers, canals and microvascular pattern

During organogenesis the mandibular condyle is divided by a fibrovascular septum, the persistence of which in the growing cartilage can lead to a bifid condyle. In this study we have evaluated the morphology of 3rd trimester human fetal temporomandibular (TMJ) specimens in order to determine the pattern of the vascular morphology associated with the layers and vascular canals (VCs) of the developing condyle (covering layers and condyle proper). Eleven

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Doubled foramen rotundum and maxillary nerve fenestration

Even though the doubled foramen rotundum (FR) can be identified once within the literature, there are no details of the contents at that level. We present here an anatomical case demonstrating the maxillary nerve (MN) duplication at the level of an unilateral doubled FR: the accessory nervous trunk of the MN separately left the trigeminal ganglion on the outer side of the MN main trunk and coursed beneath the main trunk of the MN canal, within the

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