Articolele autorului Elena Moldoveanu
Link la profilul stiintific al lui Elena Moldoveanu

Lipoprotein-associated phospholipase A2 (Lp-PLA2): a review of its role and significance as a cardiovascular biomarker

Objective: To conduct a comprehensive, systematic review of studies assessing the significance of lipoprotein-associated phospholipase A2 in cardiovascular diseases (CVDs). Material and methods: A review of the literature was performed using the search term “Lipoprotein-associated phospholipase A2 (Lp-PLA2)” and each of the following terms: “cardiovascular risk,” “cardiovascular death,” “atherosclerotic disease,” “coronary events,”

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Lipoprotein-associated phospholipase A2 activity in patients with preserved left ventricular ejection fraction

Background: A significant proportion of heart failure (HF) patients have preserved ejection fraction (EF). Considering that inflammation and oxidative stress are involved in HF evolution, we investigated lipoprotein-associated phospholipase A2 (LpPLA2), an enzyme involved in these pathophysiologic processes in relation to EF. Methods and results: The study included 208 HF patients and 20 healthy controls. HF patients with preserved EF (HFpEF) represented

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Flow cytometric assessment of circulating microparticles – towards a more objective analysis
Patients with primary antiphospholipid syndrome and coronary microvascular dysfunction – a distinct clinical subset
Acute leukemia following idiopathic chronic myelofibrosis with myeloid metaplasia
The value of the ultrastructural pattern of myeloperoxidase and plateletperoxidase in identification of two blastic cell types during transformation of a chronic myeloproliferative disorder

The value of the ultrastructural pattern of myeloperoxidase (MPO) and plateletperoxidase (PPO) staining is evaluated for the identification of the type of blastic cells during the acute transformation of a chronic myeloproliferative disorder. MPO and PPO are generally accepted as lineage specific markers for the detection of myeloid or megakaryocytic differentiation of the blast cells. The ultrastructural pattern of myeloperoxidase (MPO) and plateletperoxidase

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The significance of serum platelet-activating factor acetylhydrolase in systemic lupus erythematosus
Endothelial protection treatment in systemic lupus erythematosus
Antiphospholipid antibodies, vascular endothelial growth factor, P-selectin and lipoprotein-associated phospholipase-A2, predictors of pulmonary arterial hypertension
Circulation adiponectin level a prognostic marker for patients with heart failure