Herein, it is shown that aromatic spreading solvents can be detected using in situ UV spectroscopy at the air - water interface beyond the common accepted time for evaporation of 10 - 20 min in the preparation of a Langmuir monolayer. Toluene and benzene, even though not significantly surface active, can be detected, and their behavior as a function of time and temperature is investigated. To our knowledge, this is the first time that the vibrational

Despite the widespread growth and acceptance of particulate technology, challenges in the design, operation, and manufacturing of these systems still exists. These critical issues must be resolved so that particle technology may continue to serve as a foundation for new nano and biotechnologies. Particulate Systems in Nano- and Biotechnologies presents a summary of the revolutionizing developments that have occurred during the last decade and proposes

Gold quantum dots (AuQDs) were synthesized and electrostatically conjugated to goat-derived anti-human IgG for the purpose of detecting human IgG in solution over a broad range of concentrations. The system is able to detect human IgG by linear fluorescence quenching over a micromolar to nanomolar concentration range. We have demonstrated the specificity and a wide dynamic range of the proposed immunoassay. The quenching is a result of competitive

Amyloid peptide (Abeta) is found in the brain and blood of both healthy and diseased individuals alike. However, upon secondary structure transformation to a beta-sheet dominated conformation, the protein aggregates. These aggregates accumulate to form neuritic plaques that are implicated in the pathogenesis of Alzheimer's disease. Gold nanoparticles are excellent photon-thermal energy converters. The extinction coefficient of the surface plasmon

A glycosylphosphatidylinositol (GPI)-anchored enzyme (rat osseous plate alkaline phosphatase—OAP) was studied as monolayer (pure and mixed with lipids) at the air–water interface. Surface pressure and surface potential–area isotherms showed that the enzyme forms a stable monolayer and exhibits a liquid-expanded state even at surface pressure as high as 30 mN/m. Isotherms for mixed dimyristoylphosphatidic acid (DMPA)–OAP monolayer showed the

A synthesized peptidolipid (C18IIGLM-NH2) comprised of a single C18-saturated hydrocarbon chain connected to the amino acid sequence IIGLM terminated with the NH2 group was spread on water, which formed a stable Langmuir monolayer. The Langmuir and Langmuir-Blodgett (LB) films have been characterized by measurements of surface pressure-area (pi-A) and surface potential-area (deltaV-A) isotherms and infrared multiple-angle incidence resolution spectrometry

A synthetic peptidolipid consisted of a hydrocarbon chain with a chain length of C18 and a peptide moiety of IIGLM terminated with an amine group, designated as C18IIGLM-NH2, has been employed as a biomimic model compound of amyloid peptide for exploring molecular interaction and orientation with the use of the Langmuir monolayer and Langmuir-Blodgett film techniques. Inspired by a well-known fact that a stain reagent, Congo red (CR), binds well

The neuritic plaques formed by amyloid beta-peptide (Abeta) play a seminal role in the pathogenesis of Alzheimer's disease (AD). Abeta sequence 25-35 (GSNKGAIIGLM) is among the most frequently studied Abeta derivatives for the reason that it possesses the structural characteristic of Abeta and remains neurotoxic. Abeta(25-35) was modified with an aliphatic chain (C18) at the N-terminal of the peptide for the study of the Langmuir monolayer at the

Self-assembly property of a new liquid crystalline perylene diimide derivative, N,N'-bis[3-[2-[2-[2-(2-cyanoethoxy)ethoxy]ethoxy]ethoxy]-propyl]perylene-3,4:9,10-tetracarboxyldiimide (PPE4CN), was studied at the air/water interface by epifluorescence microscopy and on mica by environmental scanning electron microscopy (ESEM) and atomic force microscopy (AFM). The self-assembly process started at surface pressure 5 mN/m. Molecular orientation changes