In this paper, we report the spectroscopic properties of two newly synthesized phthalocyanines when substituted with short and long alkyl chains dissolved in dimethyl sulfoxide. The dyes are non-fluorescent and show a weak tendency for dimer formation. The aggregation process is not clearly visible in the absorption spectra. Therefore, steady-state and time-resolved photothermal methods were applied to evaluate the existence of the dye aggregates

Surface potential (SP) examination and FT-JR (infrared) reflection-absorption spectra were used for the characterization of interfacial effects in organic dye thin layer on solid substrates. Surface potentials of magnesium tetranaphtylporphyrin (MgTNP), magnesium or lead phthalocyanine monolayer on the water subphase were measured and the dipole moments of the investigated dyes were evaluated (1.07 D, 0.52 D and 0.31 D for MgTNP, MgPc and PbPc, respectively).

The spectroscopic characterization of synthetic porphyrins such as TPP, TSPP, ZnTSPP, etc. is reported, namely: absorption and laser induced fluorescence spectra in different solvents. Results about the photo toxicity of such photosensitizers in 5 percent DMSO in ns NaCl 0.9 percent on rats are shown proving the good acceptance of the solutions by the rats organisms with immediate perspectives for application on human patients. The second main line

Photodynamic therapy (PDT) of cancer is based on the dye- sensitized photooxidation of different biological targets in the tumoral tissue yielding to a photochemically induced cell's death. The effectiveness of this treatment method depends on the photophysical and photochemical properties of the used photosensitizer-drug during the irradiation with visible light (laser beam) and/or the ionizing radiation. The purpose of this paper is to summarize

In this study we evaluate the cytotoxicity of 5,10,15,20- tetra (4-sulfophenyl) porphyrins on a tumor cell line LSCC-SF-Mc29, obtained from a transplantable chicken hepatoma induced by the myelocytomatosis virus Mc29, a timor line LSR-SF-SR, obtained from a transplantable sarcoma in rat induced by Rous sarcoma virus strain Schmidt-Ruppin and for normal mouse cell line (BALB/c-3T3-A31) and bovine kidney cell line (MDBK). The cells were exposed to

In this study we evaluate in vitro the cytotoxic activity of two newly synthesized phthalocyanines (metallo-complexes) with absorption bands in the red part of the spectrum: zinc-tri-sulphonated phthalocyanine (ZnS4Pc). Two permanent animal tumor cell lines are used in the experiments: LSR-SF(SR)-transplantable sarcoma in rat induced by Rous sarcoma virus strain Schmidt-Ruppin and LSCC-SF(Mc29)-transplantable chicken hepatoma induced by the myelocytomatosis

Photodynamic therapy (PDT) is a treatment modality that uses a drug and light to kill tumor cells. A large number of photosensitizing agents have been tested in PDT exeperiments. The aim of the present study was to evaluate an effect of 5, 10, 15, 20-tetra (4-sulfophenyl) porphyrin (TS4PP) on viability of tumor (LSR-SF-SR, LSCC-SF-Mc29) and non-tumor (EBTr, L929) cell lines in vitro. The experiments were performed using neutral red uptake cytotoxicity

Four various phthalocyanines dyes were oriented in uniaxially stretched polymer films. Polarized absorption, fluorescence, and photoacoustic spectra were measured. From a stepwise reduction procedure, the orientation of molecules with respect to the film stretching direction as well as the orientation of absorption transition moments vectors with respect to molecular skeleton of dye were evaluated. The complexation with various metals and the attachment

The interactions of two metal-free phthalocyanines [(H2Pc) and Solar Pc (with four peripherical groups: SO2N(CH2CH2OH)2)] and of one metal substituted dye (CoPc) with resting and stimulated human peripheral blood mononuclear cells (PBMC) were compared. The absorption, fluorescence, photoacoustic and EPR spectra of both resting cells and cells stimulated by phytohaemagglutinin, incubated in dimethyl sulfoxide (DMSO) with very low or 95% water content