Articolele autorului Oana Zainea
Link la profilul stiintific al lui Oana Zainea

The Length Of Coding Sequences In A Bacterial Genome: Evidence For Short-Range Correlation

Series of coding sequence lengths extracted from the chromosome of Bacillus subtilis were subjected to detrended fluctuation analysis (DFA). The non-linear characteristic of the DFA plot was interpreted in terms of short-range correlation. The analysis was performed on series consisting of the whole chromosome coding sequences, as well as on the leading and lagging strands. These were compared to the same series subjected to a randomization procedure.

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The Statistical Physics of Microbial Genomes: Part I. Organisation of Coding Sequences in the Chromosome of Escherichia Coli

This paper shows that the correlation characteristics of coding length sequences for several strains of E. coli have a non-random organization. Although modest, this correlation at the level of the chromosome is statistically significant. The methods of analysis included spectral analysis, detrended fluctuation analysis, Hurst exponent and correlation dimension. The methods were checked up against series of data with well-known characteristics. It

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The Statistical Physics of Microbial Genomes: Part II. Organisation of Coding Sequences Involved in the Cell Divison of Escherichia Coli

The cell division coding sequences of Escherichia coli K12, O157:H7 Sakai and O157-H7 EDL933 strains were subject to a simple ranking method in connection to the origin and terminus of replication. These coding sequences were found to be distributed all along the chromosome. Data have a non-random organization. A clear grouping of genes around terminus and origin of replication is plainly observed.

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3D folding in proteins by 1H-1H Solid-State NMR magnetization exchange experiments

A systematic numerical analysis have been performed for characterizing the sensitivity of 1H-1H magnetization exchange in providing distance constraints with relevance for the investigation of protein folding by advanced solid-state NMR techniques. This was shown to increase by introducing additional initial constraints within a simplified spin-diffusion approach, for instance based on characteristic structural features of the investigated class

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The long range properties of protein structure and mobility

A correlation investigation was carried out on the series atomic coordinates (MPV) and temperature factor (Tf) respectively for protein main chains. The MPV series revealed resemblances to the corresponding Tf series in the case of human hemoglobin and HIV-1 protease. Each minor or major peak in a series had a corresponding peak in the related series. This brings a qualitative evidence for the connection of the two parameters. The series were further

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A nonlinear approach to the structure-mobility relationship in protein main chains

A correlation investigation was carried out on the series of atomic coordinates (MPV) and temperature factor (Tf), respectively for human hemoglobin and HIV-1 protease protein main chains. The MPV series revealed resemblances to the corresponding Tf series. Each minor or major peak in a series had a corresponding peak in the related series. This brings a qualitative evidence for the connection of the two parameters. The series were further subjected

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