Multifunctional PAMAM-Surface nanostructured particles organized in multimeric clusters. Potential smart delivery vehicles of bioactive species through a high selective amine-thiol bioconjugation strategy
The present work is devoted to the investigation of the polyamidoamine (PAMAM) dendrimer binding on the surface of polymer particles. Two generations of amino-terminal PAMAM macromolecules were chemically immobilized on the outer epoxy-shell of the polymer leading to nanostructured surface further available for cluster-like binding of a wide range of chemical species. The study proved that nanostructuring was successful and even enhanced by higher
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