Articolele autorului LAVINIA GEORGETA HINESCU
Link la profilul stiintific al lui LAVINIA GEORGETA HINESCU

New phthalocyanine-type compounds-synthesis, characterization and applications in gas microsensors

The paper presents the research work performed in order to obtained new original materials which reunite, in condensed systems, the phthalocyanine chromogene with azomethine type compounds. The new materials are aimed to have the cumulated properties of its precursors, being by synergism „more intelligent” then each partner reuniting the specific properties of phthalocyanines and azomethines. It also presents the manufacture and testing of resistive

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INTEGATED MICROSENSORS FOR NITRIC OXIDES DETECTION FOR BIOMEDICAL AND ENVIRONMENTAL APPLICATIONS

The paper presents the layout and the technological steps for an interdigitally integrated capacitor used for gases detection. Silicon micromachining technology is applied for manufacturing the sensor substrate. The sensitive layer used is phthalocyanine (Pc) deposed by EDL (evaporated dyes layers technique). Many solutions were found as phthalocyanine derivatives deposition technique. Considering the different sensitivities of phthalocyanines derivatives,

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Development and Validation of a Separation Method for an analgesic drug and its main metabolite from plasma

The objectives of this study were the development and validation of an extraction method for the simultaneous HPLC determination of Tramadol and its active metabolite o-desmethyltramadol (M1) in plasma in order to use it in bioequivalence studies. A reversed-phase mechanism with fluorescence detection and liquid/liquid extraction from basic plasma samples were chosen for the determination of Tramadol and M1. The bioequivalence study was made for

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Coloranti organici pentru microdispozitive bioanalitice
Semiconducting polymers based on tetraizoindole

The growing interest in the production of electronic devices are able to detect very small amounts of cellular second-messengers as NO or for monitoring gases as NO2, O2, CO2, Cl2 or other toxic gases. The metal-complex tetraizoindoles (metal phthalocyanines, MePcs) were previously shown as potential sensor materials for nitrogen oxide-sensing devices. The synthesis of nickel phthalocyanines (NiPcs), copper polyphthalocyanines (CuPcs) and aliphatic

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Semiconducting polymers based on tetraizoindole
A comparative study with different membranes and adsorptive powders on the transmembranar transfer of a Trichlorfon solution.

Development of an HPLC method for quantification of triclorfon in vitro released from acidic solution after static diffusion through cellulose membranes. Material and method. A reversed-phase mechanism with DAD detection was used to determine the amount of toxic compound released. Results. The proposed HPLC method uses a reverse-phase mechanism, a Michrosorb C18 (150x4.6mm) column, isocratic elution, 40°C column temperature. The mobile phase consists

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Trichlorfon permeation: a comparative study with different membranes and adsorptive powders

The in vitro release of trichlorphon (TCP) from acidic solutions was studied using a static diffusion cell battery, through cellulose membranes. The amount of toxic released compound decreases in the following order: cellophane (83%), cuprophan (78%) and cellulose acetate (74%). There was also studied the influence of adsorptive powders upon the decreasing amount of the released compound. We observed that the powder mixture cellulose acetate: bentonite

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Metal Complex Tetraizoidoles as Sensor Materials
Cell death pattern after angiotensin receptor (AT1) blockade in developing and mature rat kidney.

Objectives This study was designed to examine the consequences of sustained AT1 receptor inhibition on early postnatal rat kidney development and to compare the results with apoptotic index measured in adult rat kidney. Materials Wistar rats pups were randomized into 14 groups (n = 10) and daily treated with losartan (25 mg/kg body weight), for different periods (from 3 days to 2weeks). Adult rat groups were treated with same dose, and similar periods

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